AGED KIDNEYS ARE REFRACTORY TO AUTOPHAGY ACTIVATION IN A RAT MODEL OF RENAL ISCHEMIA-REPERFUSION INJURY


GFPLAIN and Multi-Source Data Assimilation Modeling: Conceptualization of a Flood Forecasting Framework Supported by Hydrogeomorphic Floodplain Rapid Mapping

Hydrologic/hydraulic models for flood risk assessment, forecasting and hindcasting have been greatly supported by the rising availability of increasingly accurate and high-resolution Earth Observation (EO) data.EO-based topographic and hydrologic open geo data are, nowadays, available on large scales.Data Assimilation (DA) models allow Early Warnin

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Pathogenic Prion Protein Isoforms Are Not Present in Cerebral Organoids Generated from Asymptomatic Donors Carrying the E200K Mutation Associated with Familial Prion Disease

Cerebral organoids (COs) are a self-organizing three-dimensional brain tissue mimicking the human cerebral cortex.COs are a promising new system for modelling pathological features Horse Fleece Quarter Sheets of neurological disorders, including prion diseases.COs expressing normal prion protein (PrPC) are susceptible to prion infection when expose

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